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Researchers have identified a potential early indicator of Alzheimer’s disease risk in the sleep patterns of otherwise healthy middle-aged individuals. The study found that people experiencing frequent micro-awakenings during sleep showed elevated genetic markers associated with the progressive neurological condition, despite exhibiting no current cognitive symptoms.
The findings suggest that seemingly minor disruptions to sleep architecture may serve as a detectable warning sign well in advance of memory loss and other cognitive decline. Scientists believe these nocturnal sleep fragmentation patterns could help identify at-risk individuals years before clinical manifestations of Alzheimer’s become apparent.
This discovery opens new avenues for early intervention and monitoring strategies in populations at higher genetic risk for the disease. Researchers emphasize that additional studies are needed to understand the mechanisms linking sleep disturbances to Alzheimer’s pathology and to determine whether addressing sleep quality could alter disease progression.
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